Signs and symptoms vary depending upon the part affected. Some of the general signs and symptoms are:

  • Persistent and unexplained  fevers, and night sweats
  • Fatigue
  • Persistent and unexplained joint or muscle pain
  • Persistent discomfort or indigestion after eating
  • Hoarseness of voice
  • Difficulty in swallowing
  • Persistent cough
  • Bowel and bladder changes
  • Skin changes like darkening or redness of the skin, yellowing, sores that does not heal, or changes to the existing moles
  • Weight changes, which includes unintended weight loss or gain
  • Thickening or lump formation under the skin