Cancer

What is Synovial Sarcoma?

One of the rare forms of soft tissue sarcomas is the synovial sarcoma. Men are twice at the risk of developing this condition than women. While 15-20 percent of the patients affected by it are adolescents, the cancer most commonly affects young people. The incidences are high in 30 years old men. This article tries to gain further insight on this subject.

What is Synovial Sarcoma?

The first term of this rare cancer refers to the location in and around the joints. When the cells making up the tissues surrounding the joints are affected by neoplasm, this cancer is diagnosed.

However, the knowledge of the type of cells which form the tumor is not available. Though two types of cells, namely the fibrous spindle and the epithelial, are present in the region, it is not clear how these cells lead to the development of cancer.

Soft tissues of the joints of the arms and legs are found to be primary sites to get affected. Knees, ankles, hips and shoulders are also affected. Its malignant nature can spread the cancer even to a distinct organ like brain in the advanced stages.

Unfortunately, the symptoms are asymptomatic or remain latent in the initial stages. Common signs of cancer like fatigue, weight loss and anemia are however present along with swelling of the common affected sites.

The method of histology is carried out to know the type of rogue cells involved with the neoplasm. The presence of cells of the synovial region along with the molecule t(x;18) confirms the disease.

Treatment of the Sarcoma of the Synovial:

In 20-70 percent cases, the cancer is cured by surgery where the rogue cells are removed along with a chunk of healthy cells in order to avoid the spread of the disease post treatment. Chemotherapy can kill the remaining malignant cells. How this treatment helps in increasing the survival rate of the patient is unclear.

However, it is found to be effective in treating advanced synovial sarcoma to some extent, according to recent studies. The benefits of radiotherapy as a treatment option are also unclear when compared to the advantages of chemotherapy.

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