What is Clear Cell Sarcoma – Symptoms, Diagnosis and Treatment

Clear cell sarcoma

is a rare form of cancer associated with the fusion of the genes EWSR1 and ATF1. It is a type of sarcoma originating from the transformed connective tissues of the body. Recurrence of this ailment is very common. People of all ages including children can develop it.

When the malignant cells are viewed under the microscope, they appear as structures similar to that of skin melanoma cancer. The tumor cells form small nests or fascicles. These structures are distinct and uniform which aid in the differentiation of this cancer from other types of sarcomas.

Symptoms of Clear Cell Sarcoma:

Development of slowly growing mass on the tendons is the sign of melanoma. However, the mass is situated deeply. The lump can be tender and cause pain only when it grows in size. Extremities of the sites like the knee, feet and ankle are the regions at high risk of developing these lumps.

Diagnosis of the Sarcoma:

The following techniques are available to find the cancer’s symptoms in the initial stages:

  • Physical Examination
  • X-rays
  • Computer tomography scans
  • Magnetic resonance imaging
  • Biopsy

As the disease spreads to fresh and remote locations of the body, it is confirmed by the following diagnostic tools:

  • Computer tomography of the chest
  • Bone scan
  • Positron Emission Tomography

If the tumor is large, premature death of the cells occur along with recurrence of the cancer. Then, the prognosis is poor. In 50 percent cases, the disease is found to reach a metastasis phase (advanced stage). The sites commonly affected in this stage are the lungs, bones and the lymph nodes.

Treatment of the Sarcoma:

Like it is the case with other cancer types, factors like site, size, stage and type of the tumor, the age and medical history of the patient play an important role in deciding the treatment.

While surgery can completely remove the tumor if it is detected early, remedies like radiation and chemotherapy are partially effective in curbing the signs of

clear cell sarcoma

in its advanced stage.

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