What is Gastrational Trophoblastic Disease (GTD)?

Gastrational trophoblastic disease (GTD)

is a rare kind of tumor condition found in women when they reach the age for conceiving children. The disease is cited as unique because the tumor in many ways mimics the state of pregnancy. The affected cells are the ones which come into existence only after the conception takes place in the uterus. In exceedingly rare cases, postmenopausal women are also found to develop this cancer.

Incidence and Risk Factors of Gastrational Trophoblastic Disease (GTD):

It is difficult to find out the number of cases of GTD every year. According to an estimate, the incidences are less in Europe and North America in comparison to Asia and Africa. Experts believe that intake of diet high in the nutrient carotene in the former regions of the world can be a possible region.

Child births outside hospitals or in homes increase the chances of this cancer in women. Such a trend of conception is prevalent in many parts of Asia and Africa.

Women below the age of 16 are six times more prone to develop GTD in comparison to those belonging to the age group 16-40 years. One in every three women above the age of 50 years stands a chance to get this cancer.

The chance of recurrence of this ailment is 1 in 100. The disease fortunately has very high rate of recovery even if the tumor is of malignant nature. In 98 percent cases, the women treated for this cancer become pregnant of the next time without any issue.


When symptoms like swollen uterus, vaginal bleeding, discomfort in the pelvis and vomiting occurs, it is time of undergo diagnosis. Initially it might involve blood test and ultrasound. It is followed by the measurement of a hormone called hCG in the blood.
During pregnancy the levels of this hormone is always high. To discriminate pregnancy with GTD, a variant of this hormone called beta hCG should be searched for. This chemical is high only when the risk of GTD is too high.

Treatment of Gastrational Trophoblastic Disease (GTD):

Evacuation of the pregnancy provides relief from all the symptoms. If the conception is not desired, the uterine contents are completely removed. Chemotherapy drugs are sufficient in treating most of the cases.

If ever very rarely the disease spreads to lungs and brain, it is a fatal condition. Radiation therapy along with chemical drugs is used to address this challenge. Women cannot conceive for one year after undergoing treatment for

Gastrational trophoblastic disease (GTD)


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